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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLRE1A
All Species:
22.42
Human Site:
T746
Identified Species:
44.85
UniProt:
Q6PJP8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJP8
NP_055696.3
1040
116422
T746
A
G
L
S
K
H
F
T
F
P
V
Y
C
S
E
Chimpanzee
Pan troglodytes
XP_508045
1040
116405
T746
A
G
L
S
K
H
F
T
F
P
V
Y
C
S
E
Rhesus Macaque
Macaca mulatta
XP_001090942
1039
116662
T745
A
G
L
S
K
H
F
T
F
P
V
Y
C
S
E
Dog
Lupus familis
XP_535018
1074
119811
T780
A
G
L
S
K
N
F
T
F
P
V
Y
C
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIC3
1026
113549
T732
A
G
L
S
K
D
F
T
R
P
V
Y
C
S
E
Rat
Rattus norvegicus
NP_001099671
1026
112807
T732
A
G
L
S
K
D
F
T
R
P
I
Y
C
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513453
994
111830
K717
N
L
V
K
S
K
L
K
V
Q
E
Q
Y
I
H
Chicken
Gallus gallus
Q5QJC4
972
108310
K695
V
K
S
K
L
R
V
K
E
Q
Y
I
N
V
L
Frog
Xenopus laevis
NP_001093331
932
103215
S656
Q
N
K
L
R
V
E
S
E
F
I
N
T
L
P
Zebra Danio
Brachydanio rerio
XP_002664006
926
102909
V650
P
M
N
T
E
C
I
V
Q
G
V
K
V
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321063
382
43088
L106
A
R
L
L
T
I
C
L
S
L
N
S
L
Y
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38961
484
55143
L208
S
R
L
L
R
L
S
L
S
V
N
P
S
S
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
93.5
71.6
N.A.
62.8
61.8
N.A.
49.7
43.4
40.2
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
96
78.9
N.A.
72.5
72.5
N.A.
63.3
58.2
55.4
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
0
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
6.6
0
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.6
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
27.1
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
50
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
9
0
17
0
9
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
50
0
34
9
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
17
9
0
9
17
% I
% Lys:
0
9
9
17
50
9
0
17
0
0
0
9
0
0
0
% K
% Leu:
0
9
67
25
9
9
9
17
0
9
0
0
9
9
17
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
9
0
0
9
0
0
0
0
17
9
9
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
50
0
9
0
0
9
% P
% Gln:
9
0
0
0
0
0
0
0
9
17
0
9
0
0
0
% Q
% Arg:
0
17
0
0
17
9
0
0
17
0
0
0
0
0
0
% R
% Ser:
9
0
9
50
9
0
9
9
17
0
0
9
9
59
0
% S
% Thr:
0
0
0
9
9
0
0
50
0
0
0
0
9
9
0
% T
% Val:
9
0
9
0
0
9
9
9
9
9
50
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
50
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _